Updated 2 October 2026 · Aurelis Peptides
Retatrutide is a peptide being developed for weight management. It works through three body signals involved in appetite and energy use. That combination has made it one of the most discussed compounds in this field.
Its strongest headline is straightforward: a controlled human trial found greater weight loss with retatrutide than with placebo.
| Main interest | Weight loss and energy balance |
|---|---|
| What studies looked at | Body-weight changes in adults |
| Study context | Human clinical trials; investigational compound |
| Listed content | 30 mg / 40 mg / 50 mg / 60 mg per unit |
What did the weight-loss study find?
A 48-week trial followed 338 adults with obesity or overweight. Participants receiving the trial retatrutide formulation lost more weight than the placebo group. This is a measured human result from a defined clinical study. Read the weight-loss study.
- Weight loss was measured over nearly a year.
- The study compared retatrutide with placebo.
- Researchers also recorded safety and tolerability.
How does retatrutide work?
Retatrutide acts on three signals called GLP-1, GIP and glucagon. In simple terms, the research brings appetite-related signalling and energy use into one peptide. Earlier animal work investigated both food intake and energy expenditure. Read the original research.
Tirzepatide acts on two of those signals. Retatrutide adds the glucagon target, which is the main difference in their scientific profiles.
Retatrutide in the Aurelis collection
The catalogue lists 30 mg, 40 mg, 50 mg and 60 mg content per unit. Retatrutide remains investigational; the Aurelis entry is research material, rather than an approved weight-management medicine. See the current product context.
Explore Retatrutide with Aurelis
Explore the Retatrutide catalogue entry and choose the listed content for your enquiry. Ask our team about the presentation and available batch documents.
Aurelis holds stock in Australia, Canada and the USA. Tell us your destination so our team can check local availability.
Enquire about Retatrutide · Open the Retatrutide catalogue profile